ALX Oncology Holdings Inc. (ALXO)


+2.92 (+60.60%)
Symbol ALXO
Price $7.725
Beta 1.719
Volume Avg. 0.16M
Market Cap 317.898M
Shares () -
52 Week Range 3.936-13.64
1y Target Est -
DCF Unlevered ALXO DCF ->
DCF Levered ALXO LDCF ->
ROE -122.89% Strong Sell
ROA -51.79% Strong Sell
Operating Margin -
Debt / Equity 4.47% Neutral
P/E -2.42 Sell
P/B 1.48 Strong Buy


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Mr. Jason W. Lettmann
NASDAQ Global Select

ALX Oncology Holdings Inc., a clinical-stage immuno-oncology company, focuses on developing therapies for patients fighting cancer. Its lead product candidate is ALX148, a CD47 blocking therapeutic that is in Phase 1b/2 clinical trial used for the treatment of myelodysplastic syndromes; and for the treatment of acute myeloid leukemia and non-Hodgkin's lymphoma, as well as a range of solid tumor indications, including head and neck squamous cell carcinoma, human epidermal growth factor receptor 2 (HER2) positive gastric/gastroesophageal junction carcinoma, HER2-expressing breast cancer, and other solid tumors. The company's pre-clinical products include ALTA-002, a SIRPa TRAAC that offers ways to engage the innate and adaptive immune response to cancer. ALX Oncology Holdings Inc. has a collaboration agreement with Merck for a Phase 2 trial evaluating ALX148 in combination with pembrolizumab with and without chemotherapy in patients with head and neck cancer; Zymeworks on a Phase 1 trial evaluating ALX148 with the HER2-targeting bispecific antibody zanidatamab in patients with HER2-expressing breast cancer and other solid tumors; and Tallac Therapeutics for the development, manufacturing and commercialization of a novel class of cancer immunotherapeutics. It also has a license agreement with Selexis SA and Crystal Bioscience, Inc. The company was founded in 2015 and is headquartered in South San Francisco, California.