• Venus Concept Inc. (NASDAQ:VERO) leads with a 483.92% increase in stock price.
• Jeffs' Brands Ltd (Nasdaq: JFBR) sees a 123.12% jump, driven by a new distribution agreement.
• Jaguar Health, Inc. (NASDAQ:JAGX) and TNL Mediagene (Nasdaq: TNMG) report significant rises of 100.13% and 68.22%, respectively, showcasing investor interest in healthcare and digital media.

In recent market trends, Venus Concept Inc. (NASDAQ:VERO) leads the top gainers with a remarkable 483.92% increase in its stock price, reaching $8.35 from a low of $1.39 over the year. This surge is driven by a major investor taking control of the company, as highlighted by NASDAQ. The company's focus on medical aesthetic and hair restoration technologies has attracted significant investor interest, with its price peaking at $12.93 during the day and a trading volume of 274,843,734, far surpassing its average.

Jeffs' Brands Ltd (Nasdaq: JFBR) follows closely with a 123.12% jump to $1.24. The company, known for its online stores on the Amazon marketplace, has seen its stock price fluctuate from a low of $0.53 to a high of $44.37 over the year. This volatility is potentially rewarding, especially after its subsidiary, KeepZone AI Inc., entered a non-exclusive distribution agreement with STI Ltd., an Israeli developer of specialized homeland security technologies. This agreement enhances KeepZone's portfolio with advanced security solutions, including under-vehicle inspection systems and explosives detection devices.

Jaguar Health, Inc. (NASDAQ:JAGX) also saw a significant rise of 100.13%, with its stock price reaching $1.53. The company's trading volume stood at 135,064,706, reflecting strong investor interest. Jaguar Health is set to present at the Lytham Partners Healthcare Investor Summit on January 15, 2026, where updates on near-term catalysts will be provided by Lisa Conte, the company's founder, president, and CEO. The company focuses on developing prescription medicines derived from rainforest plants for gastrointestinal distress.

TNL Mediagene (Nasdaq: TNMG) recorded a 68.22% increase in its stock price to $3.97. The company's performance is noteworthy, with a volume of 23,212,006, suggesting growing investor confidence. TNL Mediagene, a Tokyo-based digital media and data group, announced the successful conclusion of the Keychron Nape Pro project on its GIZMART platform. The project, developed in collaboration with Keychron, surpassed ¥300 million in gross merchandise value, showcasing the company's ability to monetize its platform through digital media-commerce initiatives.

Lastly, NextPlat Corp (NXPLW) saw its stock price rise by 64.12% to $0.09. Despite a lower trading volume of 1,419, this technology firm has demonstrated potential for growth with its innovative services in connectivity and IoT solutions. These movements highlight the dynamic nature of the market, with companies across various sectors from healthcare to technology and media showing significant gains. Investors are likely drawn to these stocks due to their innovative products, strategic expansions, or market potential, reflecting the diverse opportunities available in the current investment landscape.