Celldex Therapeutics, Inc. (CLDX)


+0.42 (+0.92%)
Symbol CLDX
Price $46.25
Beta 2.278
Volume Avg. 0.49M
Market Cap 2.178B
Shares () -
52 Week Range 19.85-48.4
1y Target Est -
DCF Unlevered CLDX DCF ->
DCF Levered CLDX LDCF ->
ROE -27.74% Sell
ROA -28.70% Sell
Operating Margin -
Debt / Equity 6.89% Neutral
P/E -
P/B 6.28 Strong Buy


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Mr. Anthony Marucci
NASDAQ Capital Market

Celldex Therapeutics, Inc., a biopharmaceutical company, engages in developing therapeutic monoclonal and bispecific antibodies for the treatment of various diseases. Its drug candidates include antibody-based therapeutics to treat patients with inflammatory diseases and various forms of cancer. The company's clinical development programs CDX-0159, a Phase I monoclonal antibody that binds the receptor tyrosine kinase KIT and inhibits its activity; CDX-1140, a human agonist monoclonal antibody targeted to CD40, a key activator of immune response, which is found on dendritic cells, macrophages, and B cells, as well as is expressed on various cancer cells; and CDX-527, a bispecific antibody, which uses the company's proprietary active anti-PD-L1 and CD27 human antibodies to couple CD27 costimulation with blockade of the PD-L1/PD-1 pathway to help prime and activate anti-tumor T cell responses through CD27 costimulation. The company has research collaboration and license agreements with University of Southampton to develop human antibodies towards CD27; Amgen Inc. with exclusive rights to CDX-301 and CD40 ligand; and Yale University. Celldex Therapeutics, Inc. was incorporated in 1983 and is headquartered in Hampton, New Jersey.