IDEAYA Biosciences, Inc. (IDYA)

$14.32

+0.52 (+3.77%)
Rating:
Recommendation:
-
Symbol IDYA
Price $14.32
Beta 1.746
Volume Avg. 0.30M
Market Cap 553.323M
Shares () -
52 Week Range 8.14-28.0
1y Target Est -
DCF Unlevered IDYA DCF ->
DCF Levered IDYA LDCF ->
ROE -19.81% Sell
ROA -15.84% Sell
Operating Margin -
Debt / Equity 24.32% Neutral
P/E -
P/B 1.91 Strong Buy
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Mr. Yujiro Hata
Healthcare
Biotechnology
NASDAQ Global Select

IDEAYA Biosciences, Inc., a synthetic lethality-focused precision medicine oncology company, focuses on the discovery and development of targeted therapeutics for patient populations selected using molecular diagnostics. The company's lead product candidates include IDE397, a methionine adenosyltransferase 2a inhibitor that is in Phase I clinical trial for patients with solid tumors having methylthioadenosine phosphorylase deletions; and IDE196, a protein kinase C inhibitor that is in Phase I/II clinical trial for genetically defined cancers having GNAQ or GNA11 gene mutations. Its preclinical pipeline includes various synthetic lethality programs targeting PARG inhibitor in tumors for patients having tumors with a defined biomarker based on genetic mutations and/or molecular signatures; Pol Theta inhibitors in tumors with BRCA or other homologous recombination deficiency mutations; and WRN inhibitors in tumors with high microsatellite instability. The company has a research collaboration agreement with Cancer Research UK and the University of Manchester to develop small molecule inhibitors of Poly (ADP-ribose) glycohydrolase; and a clinical trial collaboration and supply agreement with Pfizer Inc. for Phase I/II study in metastatic uveal melanoma, skin melanoma, and other solid tumors, as well as a strategic partnership with GlaxoSmithKline plc. IDEAYA Biosciences, Inc. was incorporated in 2015 and is headquartered in South San Francisco, California.