Turning Point Therapeutics, Inc. (TPTX)


+0.09 (+0.12%)
Symbol TPTX
Price $75.49
Beta -0.194
Volume Avg. -
Market Cap -
Shares () -
52 Week Range
1y Target Est -
DCF Unlevered TPTX DCF ->
DCF Levered TPTX LDCF ->
ROE -23.45% Sell
ROA -23.42% Sell
Operating Margin -
Debt / Equity 0.62% Neutral
P/E -13.55 Strong Sell
P/B 4.73 Strong Buy


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Dr. Athena Maria Countouriotis
NASDAQ Global Select

Turning Point Therapeutics, Inc., a clinical-stage precision oncology biopharmaceutical company, engages in designing and developing therapies that target genetic drivers of cancer. It develops a pipeline of tyrosine kinase inhibitors (TKIs) that targets genetic drivers of cancer in TKI-naïve and TKI-pretreated patients. The company's lead drug candidate repotrectinib is being evaluated in an ongoing Phase 1/2 trial called TRIDENT-1 for the treatment of patients with ROS1+ advanced non-small-cell lung cancer (NSCLC) and patients with ROS1+ and NTRK+ advanced solid tumors. It also develops TPX-0022, a MET/SRC/CSF1R inhibitor, which is in Phase 1 SHIELD-1 clinical trial for patients with advanced solid tumors harboring genetic alterations in MET; TPX-0046, a RET inhibitor that is in 1/2 SWORD-1 clinical trial for patients with advanced solid tumors harboring RET genetic alterations; and TPX-0131, an ALK inhibitor, which is in Phase 1/2 FORGE-1 study for patient with advanced or metastatic TKI-pretreated ALK-positive NSCLC. Turning Point Therapeutics, Inc. was founded in 2013 and is headquartered in San Diego, California. As of August 15, 2022, Turning Point Therapeutics, Inc. operates as a subsidiary of Bristol-Myers Squibb Company.